Background and Aim Musculoskeletal disorders are mainly prevalent among college students who experience direct contact with patients. This study aimed to determine the prevalence of musculoskeletal pains among Rehabilitation, Dentistry, and Nursing students at Arak University of Medical Sciences in 2017-2018. Methods & Materials In this cross-sectional descriptive study, 538 students of Arak University of Medical Sciences were recruited using the convenience sampling approach. Variables included age, sex, body mass index, study field, hours of using smartphone per day, and nine symptom sites being neck, shoulders, upper back, elbows, low back, wrist/hands, hips/thighs, knees, and ankles/feet. The researchers assessed the musculoskeletal pain by using the Nordic questionnaire and demographic questionnaire. Statistical analysis was performed using SPSS V. 18. Ethical Considerations The Research Ethics Committee of Arak University of Medical Sciences approved this study (Code: IR. ARAKMU. REC. 1397. 253). Results In this study, 538 students (205 males and 333 females) were studied with Mean± SD age of 22. 04± 2. 53 years old. The results showed that the prevalence of musculoskeletal pain in the spine (neck 29. 4%, upper 24. 3%, and lower back 37. 2%) was higher than in upper and lower extremities. Musculoskeletal pain in the shoulder, upper, lower back, and thigh were significantly different based on sex. Also, musculoskeletal pain in the neck and ankle, and foot were significantly different based on age (P<0. 05). There was a significant difference between musculoskeletal pain of back and ankle based on smartphone use hours per day. Conclusion This study suggested that rehabilitation, nursing, and dentistry students are at risk for musculoskeletal pain, especially in the lumbar, cervical, and upper back.